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Impact of HIV-1 Resistance-Associated Mutations on Susceptibility to Doravirine: Analysis of Real-World Clinical Isolates

Clinical management of human immunodeficiency virus type-1 (HIV-1) infection may be negatively impacted by either acquired or transmitted drug resistance. Here, we aim to extend our understanding of the impact of resistance-associated mutations (RAMs) on the susceptibility of clinical isolates to th...

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Detalles Bibliográficos
Autores principales: Asante-Appiah, Ernest, Lai, Johnny, Wan, Hong, Yang, Dongmei, Martin, Elizabeth Anne, Sklar, Peter, Hazuda, Daria, Petropoulos, Christos J., Walworth, Charles, Grobler, Jay A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597775/
https://www.ncbi.nlm.nih.gov/pubmed/34570651
http://dx.doi.org/10.1128/AAC.01216-21