The effect of S427F mutation on RXRα activity depends on its dimeric partner

RXRs are nuclear receptors acting as transcription regulators that control key cellular processes in all tissues. All type II nuclear receptors require RXRs for transcriptional activity by forming heterodimeric complexes. Recent whole-exome sequencing studies have identified the RXRα S427F hotspot m...

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Detalles Bibliográficos
Autores principales: Galdadas, Ioannis, Bonis, Vangelis, Vgenopoulou, Paraskevi, Papadourakis, Michail, Kakoulidis, Panos, Stergiou, Georgia, Cournia, Zoe, Klinakis, Apostolos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597827/
https://www.ncbi.nlm.nih.gov/pubmed/34820085
http://dx.doi.org/10.1039/d1sc04465f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597827/
https://www.ncbi.nlm.nih.gov/pubmed/34820085
http://dx.doi.org/10.1039/d1sc04465f

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