Combined Methodologies for Determining In Vitro Bioavailability of Drugs and Prediction of In Vivo Bioequivalence From Pharmaceutical Oral Formulations

With the aim of developing an in vitro model for the bioavailability (BA) prediction of drugs, we focused on the study of levonorgestrel (LVN) released by 1.5 mg generic and brand-name tablets. The developed method consisted in combining a standard dissolution test with an optimized parallel artific...

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Detalles Bibliográficos
Autores principales: De Simone, A., Davani, L., Montanari, S., Tumiatti, V., Avanessian, S., Testi, F., Andrisano, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597939/
https://www.ncbi.nlm.nih.gov/pubmed/34805090
http://dx.doi.org/10.3389/fchem.2021.741876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597939/
https://www.ncbi.nlm.nih.gov/pubmed/34805090
http://dx.doi.org/10.3389/fchem.2021.741876

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