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Examination of Gene Loss in the DNA Mismatch Repair Pathway and Its Mutational Consequences in a Fungal Phylum

The DNA mismatch repair (MMR) pathway corrects mismatched bases produced during DNA replication and is highly conserved across the tree of life, reflecting its fundamental importance for genome integrity. Loss of function in one or a few MMR genes can lead to increased mutation rates and microsatell...

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Detalles Bibliográficos
Autores principales: Phillips, Megan A, Steenwyk, Jacob L, Shen, Xing-Xing, Rokas, Antonis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8597960/
https://www.ncbi.nlm.nih.gov/pubmed/34554246
http://dx.doi.org/10.1093/gbe/evab219