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ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection

Despite antibody-dependent cellular cytotoxicity (ADCC) responses being implicated in protection from HIV-1 infection, there is limited evidence that they control virus replication. The high mutability of HIV-1 enables the virus to rapidly adapt, and thus evidence of viral escape is a very sensitive...

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Detalles Bibliográficos
Autores principales: Mielke, Dieter, Bandawe, Gama, Zheng, Jie, Jones, Jennifer, Abrahams, Melissa-Rose, Bekker, Valerie, Ochsenbauer, Christina, Garrett, Nigel, Abdool Karim, Salim, Moore, Penny L., Morris, Lynn, Montefiori, David, Anthony, Colin, Ferrari, Guido, Williamson, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598021/
https://www.ncbi.nlm.nih.gov/pubmed/34788337
http://dx.doi.org/10.1371/journal.ppat.1010046