Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly

De novo protein synthesis is required for synapse modifications underlying stable memory encoding. Yet neurons are highly compartmentalized cells and how protein synthesis can be regulated at the synapse level is unknown. Here, we characterize neuronal signaling complexes formed by the postsynaptic...

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Detalles Bibliográficos
Autores principales: Conde-Dusman, María J, Dey, Partha N, Elía-Zudaire, Óscar, Rabaneda, Luis G, García-Lira, Carmen, Grand, Teddy, Briz, Victor, Velasco, Eric R, Andero, Raül, Niñerola, Sergio, Barco, Angel, Paoletti, Pierre, Wesseling, John F, Gardoni, Fabrizio, Tavalin, Steven J, Perez-Otaño, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
https://www.ncbi.nlm.nih.gov/pubmed/34787081
http://dx.doi.org/10.7554/eLife.71575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
https://www.ncbi.nlm.nih.gov/pubmed/34787081
http://dx.doi.org/10.7554/eLife.71575

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