A convenient test system for the identification of CYP4V2 inhibitors

PURPOSE: Polymorphisms in the gene that codes for the human cytochrome P450 enzyme CYP4V2 are a cause of Bietti crystalline dystrophy (BCD). Therefore, inhibition of CYP4V2 activity may well be a cause of visual disability. However, monitoring the fatty acid hydroxylation reactions catalyzed by this...

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Detalles Bibliográficos
Autores principales: Sharma, Shishir, Liu, Sijie, Durairaj, Pradeepraj, Machalz, David, Wolber, Gerhard, Bureik, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598247/
https://www.ncbi.nlm.nih.gov/pubmed/34880593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598247/
https://www.ncbi.nlm.nih.gov/pubmed/34880593

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