Cargando…

A convenient test system for the identification of CYP4V2 inhibitors

PURPOSE: Polymorphisms in the gene that codes for the human cytochrome P450 enzyme CYP4V2 are a cause of Bietti crystalline dystrophy (BCD). Therefore, inhibition of CYP4V2 activity may well be a cause of visual disability. However, monitoring the fatty acid hydroxylation reactions catalyzed by this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sharma, Shishir, Liu, Sijie, Durairaj, Pradeepraj, Machalz, David, Wolber, Gerhard, Bureik, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598247/ https://www.ncbi.nlm.nih.gov/pubmed/34880593

Ejemplares similares

Functional Expression of All Human Sulfotransferases in Fission Yeast, Assay Development, and Structural Models for Isoforms SULT4A1 and SULT6B1
por: Sun, Yanan, et al.
Publicado: (2020)

Changes in Alprazolam Metabolism by CYP3A43 Mutants
por: Zhao, Jie, et al.
Publicado: (2022)

Corticosteroid Biosynthesis Revisited: No Direct Hydroxylation of Pregnenolone by Steroid 21-Hydroxylase
por: Loke, Steffen, et al.
Publicado: (2021)

Complete Reaction Phenotyping of Propranolol and 4-Hydroxypropranolol with the 19 Enzymes of the Human UGT1 and UGT2 Families
por: Yang, Fan, et al.
Publicado: (2022)

New luciferin-based probe substrates for human CYP26A1
por: Sharma, Shishir, et al.
Publicado: (2020)

Screening of the whole human cytochrome P450 complement (CYPome) with enzyme bag cocktails
por: Sharma, Sangeeta Shrestha, et al.
Publicado: (2020)

Mutual Influence of Human Cytochrome P450 Enzymes and UDP-Glucuronosyltransferases on Their Respective Activities in Recombinant Fission Yeast
por: Sharma, Sangeeta Shrestha, et al.
Publicado: (2023)

Mutual Modulation of the Activities of Human CYP2D6 and Four UGTs during the Metabolism of Propranolol
por: Yang, Fan, et al.
Publicado: (2023)

Versatile biocatalysis of fungal cytochrome P450 monooxygenases
por: Durairaj, Pradeepraj, et al.
Publicado: (2016)

A Convenient and Delicate Test for Albumen
Publicado: (1883)

Foundations of topology: an approach to convenient topology
por: Preuss, Gerhard
Publicado: (2002)

Convenience Behavior and Being Overweight in Adults: Development and Validation of the Convenience Behavior Questionnaire
por: Dreher, Matthias, et al.
Publicado: (2019)

Water Conveniences
Publicado: (1866)

Convenient Formulæ
Publicado: (1861)

A Convenience
Publicado: (1883)

Identification of Selective CYP3A7 and CYP3A4 Substrates and Inhibitors Using a High-Throughput Screening Platform
por: Kabir, Md, et al.
Publicado: (2022)

Discovery of novel α-amylase inhibitors using structure-based drug design
por: Al-Asri, Jamil, et al.
Publicado: (2014)

Fungal cytochrome P450 monooxygenases of Fusarium oxysporum for the synthesis of ω-hydroxy fatty acids in engineered Saccharomyces cerevisiae
por: Durairaj, Pradeepraj, et al.
Publicado: (2015)

Construction of a convenient system for easily screening inhibitors of mutated influenza virus neuraminidases()
por: Shigemori, Tomohiro, et al.
Publicado: (2013)

IDH Inhibitors and Immunotherapy for Biliary Tract Cancer: A Marriage of Convenience?
por: Brandi, Giovanni, et al.
Publicado: (2022)

A Genuine Convenience
Publicado: (1875)

A Convenient Route to 4-Carboxy-4-Anilidopiperidine Esters and Acids
por: Marton, János, et al.
Publicado: (2012)

A Convenient and Robust Test to Quantify Interocular Suppression for Children With Amblyopia
por: Chen, Hui, et al.
Publicado: (2019)

Using structure- and Ligand-based pharmacophores as filters to discriminate Human Aryl Sulfotransferase 1A1 (SUL1A1) binders into substrates and inhibitors
por: Soliman, Salwa M, et al.
Publicado: (2014)

Engineering a Reliable and Convenient SARS-CoV-2 Replicon System for Analysis of Viral RNA Synthesis and Screening of Antiviral Inhibitors
por: Luo, Yuewen, et al.
Publicado: (2021)

CYP4V2 mutation screening in an Iranian Bietti crystalline dystrophy pedigree and evidence for clustering of CYP4V2 mutations
por: Darki, Faezeh, et al.
Publicado: (2019)

CYP4 subfamily V member 2 (CYP4V2) polymorphisms were associated with ischemic stroke in Chinese Han population
por: Long, Faqing, et al.
Publicado: (2022)

COVID-19 Testing and Diagnostics: A Review of Commercialized Technologies for Cost, Convenience and Quality of Tests
por: Benda, Ashler, et al.
Publicado: (2021)

Predicting cyclooxygenase inhibition by three-dimensional pharmacophoric profiling. Part II: Identification of enzyme inhibitors from Prasaplai, a Thai traditional medicine
por: Waltenberger, Birgit, et al.
Publicado: (2011)

A CONVENIENT KETENE GENERATOR
por: Herriott, Roger M.
Publicado: (1934)

Cultures and spaces of convenience gambling
por: Egerer, Michael, et al.
Publicado: (2019)

“A Convenient Memory,” Indeed
Publicado: (1896)

A Convenient Chloroform Package
Publicado: (1909)

Screening of Human CYP1A2 and CYP3A4 Inhibitors from Seaweed In Silico and In Vitro
por: Yim, Sung-Kun, et al.
Publicado: (2020)

Identification of 1,2,4-Oxadiazoles-Based Novel EGFR Inhibitors: Molecular Dynamics Simulation-Guided Identification and in vitro ADME Studies
por: Unadkat, Vishal, et al.
Publicado: (2022)

Clonidine Stimulation Test: Is Single Best Time Point, Convenient Yet Efficacious?
por: Thakur, Darshana S., et al.
Publicado: (2018)

Smart device-based testing for medical students in Korea: satisfaction, convenience, and advantages
por: Lim, Eun Young, et al.
Publicado: (2017)

Ligand-guided homology modeling drives identification of novel histamine H3 receptor ligands
por: Schaller, David, et al.
Publicado: (2019)

Convenient Synthesis of N-Heterocycle-Fused Tetrahydro-1,4-diazepinones
por: Dzedulionytė, Karolina, et al.
Publicado: (2022)

A clinically convenient test to measure binocular balance across spatial frequency in amblyopia
por: Min, Seung Hyun, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_m83kg9jleeuenjqtj063u1ct0e