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A scalable 3D tissue culture pipeline to enable functional therapeutic screening for pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease targeting the alveolar gas exchange apparatus, leading to death by asphyxiation. IPF progresses on a tissue scale through aberrant matrix remodeling, enhanced cell contraction, and subsequent microenvironment densification. Although two ph...

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Detalles Bibliográficos
Autores principales: Cummins, Katherine A., Bitterman, Peter B., Tschumperlin, Daniel J., Wood, David K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598262/
https://www.ncbi.nlm.nih.gov/pubmed/34805716
http://dx.doi.org/10.1063/5.0054967