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Δ (9)-Tetrahydrocannabinol During Adolescence Reprograms the Nucleus Accumbens Transcriptome, Affecting Reward Processing, Impulsivity, and Specific Aspects of Cocaine Addiction-Like Behavior in a Sex-Dependent Manner

BACKGROUND: Cannabis exposure during adolescence is associated with emotional and motivational alterations that may entail an enhanced risk of developing psychiatric disorders. In rodent models, exposure to cannabinoids during adolescence leads to increased self-administration of opiates and cocaine...

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Detalles Bibliográficos
Autores principales: Orihuel, Javier, Capellán, Roberto, Roura-Martínez, David, Ucha, Marcos, Ambrosio, Emilio, Higuera-Matas, Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598305/
https://www.ncbi.nlm.nih.gov/pubmed/34436576
http://dx.doi.org/10.1093/ijnp/pyab058