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Dual roles of SIRT1 in the BAX switch through the P53 module: A mathematical modeling study
SIRT1 is a multifunctional deacetylase that participates in a variety of cellular physiological processes to cope with stress. The anticancer protein P53 is an important target of SIRT1. It has been found that SIRT1 is involved in apoptosis by regulating the activity and intracellular location of P5...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8598928/ https://www.ncbi.nlm.nih.gov/pubmed/34849192 http://dx.doi.org/10.1016/j.csbj.2021.09.033 |