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Glucosylceramide synthase deficiency in the heart compromises β1-adrenergic receptor trafficking

AIMS : Cardiac injury and remodelling are associated with the rearrangement of cardiac lipids. Glycosphingolipids are membrane lipids that are important for cellular structure and function, and cardiac dysfunction is a characteristic of rare monogenic diseases with defects in glycosphingolipid synth...

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Detalles Bibliográficos
Autores principales: Andersson, Linda, Cinato, Mathieu, Mardani, Ismena, Miljanovic, Azra, Arif, Muhammad, Koh, Ara, Lindbom, Malin, Laudette, Marion, Bollano, Entela, Omerovic, Elmir, Klevstig, Martina, Henricsson, Marcus, Fogelstrand, Per, Swärd, Karl, Ekstrand, Matias, Levin, Max, Wikström, Johannes, Doran, Stephen, Hyötyläinen, Tuulia, Sinisalu, Lisanna, Orešič, Matej, Tivesten, Åsa, Adiels, Martin, Bergo, Martin O, Proia, Richard, Mardinoglu, Adil, Jeppsson, Anders, Borén, Jan, Levin, Malin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599074/
https://www.ncbi.nlm.nih.gov/pubmed/34297830
http://dx.doi.org/10.1093/eurheartj/ehab412