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Nigral diffusivity, but not free water, correlates with iron content in Parkinson’s disease

The loss of melanized neurons in the substantia nigra pars compacta is a primary feature in Parkinson’s disease. Iron deposition occurs in conjunction with this loss. Loss of nigral neurons should remove barriers for diffusion and increase diffusivity of water molecules in regions undergoing this lo...

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Detalles Bibliográficos
Autores principales: Langley, Jason, Huddleston, Daniel E, Hu, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599079/
https://www.ncbi.nlm.nih.gov/pubmed/34805996
http://dx.doi.org/10.1093/braincomms/fcab251