Immune system cells from COVID-19 patients display compromised mitochondrial-nuclear expression co-regulation and rewiring toward glycolysis

Mitochondria are pivotal for bioenergetics, as well as in cellular response to viral infections. Nevertheless, their role in COVID-19 was largely overlooked. Here, we analyzed available bulk RNA-seq datasets from COVID-19 patients and corresponding healthy controls (three blood datasets, N = 48 heal...

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Detalles Bibliográficos
Autores principales: Medini, Hadar, Zirman, Amit, Mishmar, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599136/
https://www.ncbi.nlm.nih.gov/pubmed/34812416
http://dx.doi.org/10.1016/j.isci.2021.103471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599136/
https://www.ncbi.nlm.nih.gov/pubmed/34812416
http://dx.doi.org/10.1016/j.isci.2021.103471

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