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C-Reactive Protein Protects Against Acetaminophen-Induced Liver Injury by Preventing Complement Overactivation

BACKGROUND AND AIMS: C-reactive protein (CRP) is a hepatocyte-produced marker of inflammation yet with undefined function in liver injury. We aimed to examine the role of CRP in acetaminophen-induced liver injury (AILI). METHODS: The effects of CRP in AILI were investigated using CRP knockout mice a...

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Detalles Bibliográficos
Autores principales: Li, Hai-Yun, Tang, Zhao-Ming, Wang, Zhe, Lv, Jian-Min, Liu, Xiao-Ling, Liang, Yu-Lin, Cheng, Bin, Gao, Ning, Ji, Shang-Rong, Wu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599171/
https://www.ncbi.nlm.nih.gov/pubmed/34536564
http://dx.doi.org/10.1016/j.jcmgh.2021.09.003