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Berberine Alleviates Insulin Resistance and Inflammation via Inhibiting the LTB4–BLT1 Axis

Background: Chronic low-grade inflammation is recognized as a key pathophysiological mechanism of insulin resistance. Leukotriene B4 (LTB4), a molecule derived from arachidonic acid, is a potent neutrophil chemoattractant. The excessive amount of LTB4 that is combined with its receptor BLT1 can caus...

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Detalles Bibliográficos
Autores principales: Gong, Minmin, Duan, Huiyan, Wu, Fan, Ren, Yanlin, Gong, Jing, Xu, Lijun, Lu, Fuer, Wang, Dingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599302/
https://www.ncbi.nlm.nih.gov/pubmed/34803675
http://dx.doi.org/10.3389/fphar.2021.722360