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Impact of repeated co-treatment with escitalopram and aripiprazole on the schizophrenia-like behaviors and BDNF mRNA expression in the adult Sprague–Dawley rats exposed to glutathione deficit during early postnatal development of the brain

BACKGROUND: Preclinical and clinical studies have indicated that impaired endogenous synthesis of glutathione during early postnatal development plays a significant role in the pathophysiology of schizophrenia. Moreover, some studies have suggested that antidepressants are able to increase the activ...

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Detalles Bibliográficos
Autores principales: Lech, Marta A., Kamińska, Kinga, Leśkiewicz, Monika, Lorenc-Koci, Elżbieta, Rogóż, Zofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599398/
https://www.ncbi.nlm.nih.gov/pubmed/34398437
http://dx.doi.org/10.1007/s43440-021-00318-z