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Cyclodextrins Exert a Ligand-like Current Inhibitory Effect on the K(V)1.3 Ion Channel Independent of Membrane Cholesterol Extraction

Cyclodextrins (CDs) are cyclic oligosaccharides capable of forming water-soluble complexes with a variety of otherwise poorly soluble molecules including cholesterol and different drugs. Consistently, CDs are widely used in research and clinical practice to deplete cholesterol from cellular membrane...

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Detalles Bibliográficos
Autores principales: Kovacs, Tamas, Sohajda, Tamas, Szente, Lajos, Nagy, Peter, Panyi, Gyorgy, Varga, Zoltan, Zakany, Florina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599428/
https://www.ncbi.nlm.nih.gov/pubmed/34805269
http://dx.doi.org/10.3389/fmolb.2021.735357