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Cyclodextrins Exert a Ligand-like Current Inhibitory Effect on the K(V)1.3 Ion Channel Independent of Membrane Cholesterol Extraction
Cyclodextrins (CDs) are cyclic oligosaccharides capable of forming water-soluble complexes with a variety of otherwise poorly soluble molecules including cholesterol and different drugs. Consistently, CDs are widely used in research and clinical practice to deplete cholesterol from cellular membrane...
Autores principales: | Kovacs, Tamas, Sohajda, Tamas, Szente, Lajos, Nagy, Peter, Panyi, Gyorgy, Varga, Zoltan, Zakany, Florina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599428/ https://www.ncbi.nlm.nih.gov/pubmed/34805269 http://dx.doi.org/10.3389/fmolb.2021.735357 |
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