TFCP2 Overcomes Senescence by Cooperating With SREBP2 to Activate Cholesterol Synthesis in Pancreatic Cancer

KRAS mutation is very common in pancreatic cancer. How pancreatic cancer cells overcome oncogene-induced senescence is not fully understood. Our previous studies showed that up-regulation of TFCP2 (transcription factor CP2) in pancreatic cancer promoted the growth and metastasis of pancreatic cancer...

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Detalles Bibliográficos
Autores principales: Zhang, Dexiang, Lu, Pinxiang, Zhu, Kaihua, Wu, Haixia, Dai, Yuedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599447/
https://www.ncbi.nlm.nih.gov/pubmed/34804919
http://dx.doi.org/10.3389/fonc.2021.724437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599447/
https://www.ncbi.nlm.nih.gov/pubmed/34804919
http://dx.doi.org/10.3389/fonc.2021.724437

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