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Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm

The poles of the heart and branchiomeric muscles of the face and neck are formed from the cardiopharyngeal mesoderm within the pharyngeal apparatus. They are disrupted in patients with 22q11.2 deletion syndrome, due to haploinsufficiency of TBX1, encoding a T-box transcription factor. Here, using si...

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Detalles Bibliográficos
Autores principales: Nomaru, Hiroko, Liu, Yang, De Bono, Christopher, Righelli, Dario, Cirino, Andrea, Wang, Wei, Song, Hansoo, Racedo, Silvia E., Dantas, Anelisa G., Zhang, Lu, Cai, Chen-Leng, Angelini, Claudia, Christiaen, Lionel, Kelly, Robert G., Baldini, Antonio, Zheng, Deyou, Morrow, Bernice E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599455/
https://www.ncbi.nlm.nih.gov/pubmed/34789765
http://dx.doi.org/10.1038/s41467-021-26966-6