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Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm
The poles of the heart and branchiomeric muscles of the face and neck are formed from the cardiopharyngeal mesoderm within the pharyngeal apparatus. They are disrupted in patients with 22q11.2 deletion syndrome, due to haploinsufficiency of TBX1, encoding a T-box transcription factor. Here, using si...
Autores principales: | Nomaru, Hiroko, Liu, Yang, De Bono, Christopher, Righelli, Dario, Cirino, Andrea, Wang, Wei, Song, Hansoo, Racedo, Silvia E., Dantas, Anelisa G., Zhang, Lu, Cai, Chen-Leng, Angelini, Claudia, Christiaen, Lionel, Kelly, Robert G., Baldini, Antonio, Zheng, Deyou, Morrow, Bernice E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599455/ https://www.ncbi.nlm.nih.gov/pubmed/34789765 http://dx.doi.org/10.1038/s41467-021-26966-6 |
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