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Focused Proteomics Analysis of Habu Snake (Protobothrops flavoviridis) Venom Using Antivenom-Based Affinity Chromatography Reveals Novel Myonecrosis-Enhancing Activity of Thrombin-Like Serine Proteases

Snakebites are one of the major causes of death and long-term disability in the developing countries due to the presence of various bioactive peptides and proteins in snake venom. In Japan, the venom of the habu snake (Protobothrops flavoviridis) causes severe permanent damage due to its myonecrotic...

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Detalles Bibliográficos
Autores principales: Ogawa, Tomohisa, Tobishima, Yu, Kamata, Shizuka, Matsuda, Youhei, Muramoto, Koji, Hidaka, Masafumi, Futai, Eugene, Kuraishi, Takeshi, Yokota, Shinichi, Ohno, Motonori, Hattori, Shosaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599580/
https://www.ncbi.nlm.nih.gov/pubmed/34803710
http://dx.doi.org/10.3389/fphar.2021.766406