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Precision therapy for RET-altered cancers with RET inhibitors

Rearranged during transfection (RET) is involved in the physiological development of some organ systems. Activating RET alterations via either gene fusions or point mutations are potent oncogenic drivers in non-small cell lung cancer, thyroid cancer, and in multiple diverse cancers. RET-altered canc...

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Detalles Bibliográficos
Autores principales: Thein, Kyaw Z., Velcheti, Vamsidhar, Mooers, Blaine H.M., Wu, Jie, Subbiah, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599646/
https://www.ncbi.nlm.nih.gov/pubmed/34391699
http://dx.doi.org/10.1016/j.trecan.2021.07.003