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Need for discriminating between diagnostic and screening efficacy to estimate a biomarker based on case control and cohort studies
This study proposes the comprehensive index of biomarker (CIB), based on the consistency of a biomarker in case control (Youden index, J) and cohort studies (Crc), to evaluate biomarker efficacy. CIB was calculated as the mean of J and Crc. Analysis of the effect of sensitivity and specificity on CI...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599673/ https://www.ncbi.nlm.nih.gov/pubmed/34789793 http://dx.doi.org/10.1038/s41598-021-01904-0 |