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PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure

Phosphatase and Tensin Homolog on chromosome Ten (PTEN) has emerged as a key protein that governs the response to kidney injury. Notably, renal adaptive repair is important for preventing acute kidney injury (AKI) to chronic kidney disease (CKD) transition. To test the role of PTEN in renal repair a...

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Detalles Bibliográficos
Autores principales: Wang, Huizhen, Wang, Yifan, Wang, Xin, Huang, Huimi, Bao, Jingfu, Zhong, Wenhui, Li, Aiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599682/
https://www.ncbi.nlm.nih.gov/pubmed/34789720
http://dx.doi.org/10.1038/s41419-021-04372-6