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Transliteration of synthetic genetic enzymes

Functional nucleic acids lose activity when their sequence is prepared in the backbone architecture of a different genetic polymer. The only known exception to this rule is a subset of aptamers whose binding mechanism involves G-quadruplex formation. We refer to such examples as transliteration—a sy...

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Detalles Bibliográficos
Autores principales: Wang, Yajun, Liu, Xiaolin, Shehabat, Mouhamad, Chim, Nicholas, Chaput, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599711/
https://www.ncbi.nlm.nih.gov/pubmed/34634814
http://dx.doi.org/10.1093/nar/gkab923