Human MettL3-MettL14 RNA adenine methyltransferase complex is active on double-stranded DNA containing lesions

MettL3-MettL14 methyltransferase complex has been studied widely for its role in RNA adenine methylation. This complex is also recruited to UV- and X-ray exposed DNA damaged sites, and its methyltransfer activity is required for subsequent DNA repair, though in theory this could result from RNA meth...

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Detalles Bibliográficos
Autores principales: Yu, Dan, Horton, John R, Yang, Jie, Hajian, Taraneh, Vedadi, Masoud, Sagum, Cari A, Bedford, Mark T, Blumenthal, Robert M, Zhang, Xing, Cheng, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599731/
https://www.ncbi.nlm.nih.gov/pubmed/34086966
http://dx.doi.org/10.1093/nar/gkab460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599731/
https://www.ncbi.nlm.nih.gov/pubmed/34086966
http://dx.doi.org/10.1093/nar/gkab460

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