MicroDNA levels are dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA damage

Extrachromosomal circular DNA (eccDNA) are present within all eukaryotic organisms and actively contribute to gene expression changes. MicroDNA (200-1000bp) are the most abundant type of eccDNA and can amplify tRNA, microRNA, and novel si-like RNA sequences. Due to the heterogeneity of microDNA and...

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Detalles Bibliográficos
Autores principales: Paulsen, Teressa, Malapati, Pumoli, Shibata, Yoshiyuki, Wilson, Briana, Eki, Rebeka, Benamar, Mouadh, Abbas, Tarek, Dutta, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599734/
https://www.ncbi.nlm.nih.gov/pubmed/34718766
http://dx.doi.org/10.1093/nar/gkab984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599734/
https://www.ncbi.nlm.nih.gov/pubmed/34718766
http://dx.doi.org/10.1093/nar/gkab984

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