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MicroDNA levels are dependent on MMEJ, repressed by c-NHEJ pathway, and stimulated by DNA damage
Extrachromosomal circular DNA (eccDNA) are present within all eukaryotic organisms and actively contribute to gene expression changes. MicroDNA (200-1000bp) are the most abundant type of eccDNA and can amplify tRNA, microRNA, and novel si-like RNA sequences. Due to the heterogeneity of microDNA and...
Autores principales: | Paulsen, Teressa, Malapati, Pumoli, Shibata, Yoshiyuki, Wilson, Briana, Eki, Rebeka, Benamar, Mouadh, Abbas, Tarek, Dutta, Anindya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599734/ https://www.ncbi.nlm.nih.gov/pubmed/34718766 http://dx.doi.org/10.1093/nar/gkab984 |
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