ENDO-Pore: high-throughput linked-end mapping of single DNA cleavage events using nanopore sequencing

Mapping the precise position of DNA cleavage events plays a key role in determining the mechanism and function of endonucleases. ENDO-Pore is a high-throughput nanopore-based method that allows the time resolved mapping single molecule DNA cleavage events in vitro. Following linearisation of a circu...

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Detalles Bibliográficos
Autores principales: Torres Montaguth, Oscar E, Cross, Stephen J, Ingram, Kincaid W A, Lee, Laura, Diffin, Fiona M, Szczelkun, Mark D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599736/
https://www.ncbi.nlm.nih.gov/pubmed/34417616
http://dx.doi.org/10.1093/nar/gkab727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599736/
https://www.ncbi.nlm.nih.gov/pubmed/34417616
http://dx.doi.org/10.1093/nar/gkab727

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