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ENDO-Pore: high-throughput linked-end mapping of single DNA cleavage events using nanopore sequencing
Mapping the precise position of DNA cleavage events plays a key role in determining the mechanism and function of endonucleases. ENDO-Pore is a high-throughput nanopore-based method that allows the time resolved mapping single molecule DNA cleavage events in vitro. Following linearisation of a circu...
Autores principales: | Torres Montaguth, Oscar E, Cross, Stephen J, Ingram, Kincaid W A, Lee, Laura, Diffin, Fiona M, Szczelkun, Mark D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599736/ https://www.ncbi.nlm.nih.gov/pubmed/34417616 http://dx.doi.org/10.1093/nar/gkab727 |
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