An integrative NMR-SAXS approach for structural determination of large RNAs defines the substrate-free state of a trans-cleaving Neurospora Varkud Satellite ribozyme

The divide-and-conquer strategy is commonly used for protein structure determination, but its applications to high-resolution structure determination of RNAs have been limited. Here, we introduce an integrative approach based on the divide-and-conquer strategy that was undertaken to determine the so...

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Detalles Bibliográficos
Autores principales: Dagenais, Pierre, Desjardins, Geneviève, Legault, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599749/
https://www.ncbi.nlm.nih.gov/pubmed/34718697
http://dx.doi.org/10.1093/nar/gkab963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599749/
https://www.ncbi.nlm.nih.gov/pubmed/34718697
http://dx.doi.org/10.1093/nar/gkab963

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