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SuperSelective primer pairs for sensitive detection of rare somatic mutations

SuperSelective primers, by virtue of their unique design, enable the selective exponential amplification of rare DNA fragments containing somatic mutations in the presence of abundant closely related wild-type DNA fragments. However, when a SuperSelective primer is used in conjunction with a convent...

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Detalles Bibliográficos
Autores principales: Kramer, Fred Russell, Vargas, Diana Yaneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599793/
https://www.ncbi.nlm.nih.gov/pubmed/34789731
http://dx.doi.org/10.1038/s41598-021-00920-4