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SuperSelective primer pairs for sensitive detection of rare somatic mutations
SuperSelective primers, by virtue of their unique design, enable the selective exponential amplification of rare DNA fragments containing somatic mutations in the presence of abundant closely related wild-type DNA fragments. However, when a SuperSelective primer is used in conjunction with a convent...
Autores principales: | Kramer, Fred Russell, Vargas, Diana Yaneth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599793/ https://www.ncbi.nlm.nih.gov/pubmed/34789731 http://dx.doi.org/10.1038/s41598-021-00920-4 |
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