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Enhancer architecture-dependent multilayered transcriptional regulation orchestrates RA signaling-induced early lineage differentiation of ESCs

Signaling pathway-driven target gene transcription is critical for fate determination of embryonic stem cells (ESCs), but enhancer-dependent transcriptional regulation in these processes remains poorly understood. Here, we report enhancer architecture-dependent multilayered transcriptional regulatio...

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Detalles Bibliográficos
Autores principales: Su, Guangsong, Wang, Wenbin, Zhao, Xueyuan, Chen, Jun, Zheng, Jian, Liu, Man, Bi, Jinfang, Guo, Dianhao, Chen, Bohan, Zhao, Zhongfang, Shi, Jiandang, Zhang, Lei, Lu, Wange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599802/
https://www.ncbi.nlm.nih.gov/pubmed/34723340
http://dx.doi.org/10.1093/nar/gkab1001