Cargando…
Enhancer architecture-dependent multilayered transcriptional regulation orchestrates RA signaling-induced early lineage differentiation of ESCs
Signaling pathway-driven target gene transcription is critical for fate determination of embryonic stem cells (ESCs), but enhancer-dependent transcriptional regulation in these processes remains poorly understood. Here, we report enhancer architecture-dependent multilayered transcriptional regulatio...
Autores principales: | Su, Guangsong, Wang, Wenbin, Zhao, Xueyuan, Chen, Jun, Zheng, Jian, Liu, Man, Bi, Jinfang, Guo, Dianhao, Chen, Bohan, Zhao, Zhongfang, Shi, Jiandang, Zhang, Lei, Lu, Wange |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599802/ https://www.ncbi.nlm.nih.gov/pubmed/34723340 http://dx.doi.org/10.1093/nar/gkab1001 |
Ejemplares similares
-
A distal enhancer maintaining Hoxa1 expression orchestrates retinoic acid-induced early ESCs differentiation
por: Su, Guangsong, et al.
Publicado: (2019) -
KLF4 inhibits early neural differentiation of ESCs by coordinating specific 3D chromatin structure
por: Bi, Jinfang, et al.
Publicado: (2022) -
CTCF-binding element regulates ESC differentiation via orchestrating long-range chromatin interaction between enhancers and HoxA
por: Su, Guangsong, et al.
Publicado: (2021) -
Decoding the dynamic DNA methylation and hydroxymethylation landscapes in endodermal lineage intermediates during pancreatic differentiation of hESC
por: Li, Jia, et al.
Publicado: (2018) -
N
(6)-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential
por: Yang, Dandan, et al.
Publicado: (2018)