Cargando…

Personalizing Breast Cancer Screening Based on Polygenic Risk and Family History

BACKGROUND: We assessed the clinical utility of a first-degree breast cancer family history and polygenic risk score (PRS) to inform screening decisions among women aged 30-50 years. METHODS: Two established breast cancer models evaluated digital mammography screening strategies in the 1985 US birth...

Descripción completa

Detalles Bibliográficos
Autores principales: van den Broek, Jeroen J, Schechter, Clyde B, van Ravesteyn, Nicolien T, Janssens, A Cecile J W, Wolfson, Michael C, Trentham-Dietz, Amy, Simard, Jacques, Easton, Douglas F, Mandelblatt, Jeanne S, Kraft, Peter, de Koning, Harry J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599807/
https://www.ncbi.nlm.nih.gov/pubmed/32853342
http://dx.doi.org/10.1093/jnci/djaa127