Cargando…

Large-scale movement of eIF3 domains during translation initiation modulate start codon selection

The eukaryotic initiation factor 3 (eIF3) complex is involved in every step of translation initiation, but there is limited understanding of its molecular functions. Here, we present a single particle electron cryomicroscopy (cryo-EM) reconstruction of yeast 48S ribosomal preinitiation complex (PIC)...

Descripción completa

Detalles Bibliográficos
Autores principales: Llácer, Jose L, Hussain, Tanweer, Dong, Jinsheng, Villamayor, Laura, Gordiyenko, Yuliya, Hinnebusch, Alan G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599844/
https://www.ncbi.nlm.nih.gov/pubmed/34648019
http://dx.doi.org/10.1093/nar/gkab908