GRP78/BiP determines senescence evasion cell fate after cisplatin-based chemotherapy

Cisplatin (CDDP) induces senescence characterized by senescence-associated secretory phenotypes (SASP) and the unfolded protein response (UPR). In this study, we investigated the proteins related to the UPR during the senescence cell fate. Strikingly, we found that one of the critical ER-resident pr...

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Detalles Bibliográficos
Autores principales: Ei, Zin Zin, Choochuay, Kanuengnit, Tubsuwan, Alisa, Pinkaew, Decha, Suksomtip, Maneewan, Vinayanuwattikun, Chanida, Chanvorachote, Pithi, Chunhacha, Preedakorn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599848/
https://www.ncbi.nlm.nih.gov/pubmed/34789798
http://dx.doi.org/10.1038/s41598-021-01540-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599848/
https://www.ncbi.nlm.nih.gov/pubmed/34789798
http://dx.doi.org/10.1038/s41598-021-01540-8

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