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GRP78/BiP determines senescence evasion cell fate after cisplatin-based chemotherapy
Cisplatin (CDDP) induces senescence characterized by senescence-associated secretory phenotypes (SASP) and the unfolded protein response (UPR). In this study, we investigated the proteins related to the UPR during the senescence cell fate. Strikingly, we found that one of the critical ER-resident pr...
Autores principales: | Ei, Zin Zin, Choochuay, Kanuengnit, Tubsuwan, Alisa, Pinkaew, Decha, Suksomtip, Maneewan, Vinayanuwattikun, Chanida, Chanvorachote, Pithi, Chunhacha, Preedakorn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599848/ https://www.ncbi.nlm.nih.gov/pubmed/34789798 http://dx.doi.org/10.1038/s41598-021-01540-8 |
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