Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation

Pupylation is the post-translational modification of lysine side chains with prokaryotic ubiquitin-like protein (Pup) that targets proteins for proteasomal degradation in mycobacteria and other members of Actinobacteria. Pup ligase PafA and depupylase Dop are the two enzymes acting in this pathway....

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Detalles Bibliográficos
Autores principales: Cui, Hengjun, Müller, Andreas U., Leibundgut, Marc, Tian, Jiawen, Ban, Nenad, Weber-Ban, Eilika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599861/
https://www.ncbi.nlm.nih.gov/pubmed/34789727
http://dx.doi.org/10.1038/s41467-021-26848-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599861/
https://www.ncbi.nlm.nih.gov/pubmed/34789727
http://dx.doi.org/10.1038/s41467-021-26848-x

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