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Structures of prokaryotic ubiquitin-like protein Pup in complex with depupylase Dop reveal the mechanism of catalytic phosphate formation
Pupylation is the post-translational modification of lysine side chains with prokaryotic ubiquitin-like protein (Pup) that targets proteins for proteasomal degradation in mycobacteria and other members of Actinobacteria. Pup ligase PafA and depupylase Dop are the two enzymes acting in this pathway....
Autores principales: | Cui, Hengjun, Müller, Andreas U., Leibundgut, Marc, Tian, Jiawen, Ban, Nenad, Weber-Ban, Eilika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599861/ https://www.ncbi.nlm.nih.gov/pubmed/34789727 http://dx.doi.org/10.1038/s41467-021-26848-x |
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