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Nanomechanics of negatively supercoiled diaminopurine-substituted DNA

Single molecule experiments have demonstrated a progressive transition from a B- to an L-form helix as DNA is gently stretched and progressively unwound. The particular sequence of a DNA segment defines both base stacking and hydrogen bonding that affect the partitioning and conformations of the two...

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Detalles Bibliográficos
Autores principales: Salerno, Domenico, Marrano, Claudia Adriana, Cassina, Valeria, Cristofalo, Matteo, Shao, Qing, Finzi, Laura, Mantegazza, Francesco, Dunlap, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599871/
https://www.ncbi.nlm.nih.gov/pubmed/34718727
http://dx.doi.org/10.1093/nar/gkab982