The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface

The human pseudouridine synthase PUS7 is a versatile RNA modification enzyme targeting many RNAs thereby playing a critical role in development and brain function. Whereas all target RNAs of PUS7 share a consensus sequence, additional recognition elements are likely required, and the structural basi...

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Detalles Bibliográficos
Autores principales: Guegueniat, Julia, Halabelian, Levon, Zeng, Hong, Dong, Aiping, Li, Yanjun, Wu, Hong, Arrowsmith, Cheryl H, Kothe, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599909/
https://www.ncbi.nlm.nih.gov/pubmed/34718722
http://dx.doi.org/10.1093/nar/gkab934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599909/
https://www.ncbi.nlm.nih.gov/pubmed/34718722
http://dx.doi.org/10.1093/nar/gkab934

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