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The human pseudouridine synthase PUS7 recognizes RNA with an extended multi-domain binding surface
The human pseudouridine synthase PUS7 is a versatile RNA modification enzyme targeting many RNAs thereby playing a critical role in development and brain function. Whereas all target RNAs of PUS7 share a consensus sequence, additional recognition elements are likely required, and the structural basi...
Autores principales: | Guegueniat, Julia, Halabelian, Levon, Zeng, Hong, Dong, Aiping, Li, Yanjun, Wu, Hong, Arrowsmith, Cheryl H, Kothe, Ute |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599909/ https://www.ncbi.nlm.nih.gov/pubmed/34718722 http://dx.doi.org/10.1093/nar/gkab934 |
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