DNA sequence and methylation prescribe the inside-out conformational dynamics and bending energetics of DNA minicircles

Eukaryotic genome and methylome encode DNA fragments’ propensity to form nucleosome particles. Although the mechanical properties of DNA possibly orchestrate such encoding, the definite link between ‘omics’ and DNA energetics has remained elusive. Here, we bridge the divide by examining the sequence...

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Detalles Bibliográficos
Autores principales: Yoo, Jejoong, Park, Sangwoo, Maffeo, Christopher, Ha, Taekjip, Aksimentiev, Aleksei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599915/
https://www.ncbi.nlm.nih.gov/pubmed/34718725
http://dx.doi.org/10.1093/nar/gkab967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599915/
https://www.ncbi.nlm.nih.gov/pubmed/34718725
http://dx.doi.org/10.1093/nar/gkab967

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