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DNA sequence and methylation prescribe the inside-out conformational dynamics and bending energetics of DNA minicircles
Eukaryotic genome and methylome encode DNA fragments’ propensity to form nucleosome particles. Although the mechanical properties of DNA possibly orchestrate such encoding, the definite link between ‘omics’ and DNA energetics has remained elusive. Here, we bridge the divide by examining the sequence...
Autores principales: | Yoo, Jejoong, Park, Sangwoo, Maffeo, Christopher, Ha, Taekjip, Aksimentiev, Aleksei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599915/ https://www.ncbi.nlm.nih.gov/pubmed/34718725 http://dx.doi.org/10.1093/nar/gkab967 |
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