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Evaluation of the OsTIR1 and AtAFB2 AID Systems for Genome Architectural Protein Degradation in Mammalian Cells

The auxin-inducible degron (AID) system is a promising tool for dynamic protein degradation. In mammalian cells, this approach has become indispensable to study fundamental molecular functions, such as replication, chromatin dynamics, or transcription, which are otherwise difficult to dissect. We pr...

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Detalles Bibliográficos
Autores principales: Yunusova, Anastasia, Smirnov, Alexander, Shnaider, Tatiana, Lukyanchikova, Varvara, Afonnikova, Svetlana, Battulin, Nariman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599953/
https://www.ncbi.nlm.nih.gov/pubmed/34805274
http://dx.doi.org/10.3389/fmolb.2021.757394