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Mechanistic Computational Models of Epithelial Cell Transporters-the Adorned Heroes of Pharmacokinetics

Epithelial membrane transporter kinetics portray an irrefutable role in solute transport in and out of cells. Mechanistic models are used to investigate the transport of solutes at the organ, tissue, cell or membrane scale. Here, we review the recent advancements in using computational models to inv...

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Detalles Bibliográficos
Autores principales: King, Jasia, Giselbrecht, Stefan, Truckenmüller, Roman, Carlier, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8599978/
https://www.ncbi.nlm.nih.gov/pubmed/34803720
http://dx.doi.org/10.3389/fphar.2021.780620